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KMID : 1123920070210010231
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Korean Journal of Oriental Physiology and Pathology
2007 Volume.21 No. 1 p.231 ~ p.234
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Isolation and Antimicrobial Activity of Dichlororinated Bibenzyl Compound
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Na Young-Soon
Lee Jae-Sook
Baek Seung-Hwa
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Abstract
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Dichlororinated bibenzyl compound (4) has been isolated from the New Zealand liverwort. This compound was elucidated using 1D/2D-NMR and mass spectral method. The compound (3) inhibited the growth of the Gram positive bacterium Bacillus subtilis ATCC 19659, (2 mm inhibition zone and 2 mm inhibition zone at 30 g/disc), Candida albicans ATCC 14053, (2 mm inhibition zone and 2 mm inhibition zone at 30 g/disc), and the dermatophytic fungi Trichophyton mentagrophytes ATCC 28185, (12 mm inhibition zone at 30 g/disc) and Cladosporium resinae ATCC 52833 (2 mm inhibition zone at 30 g/disc). This bibenzyl compound (4) exhibited antimicrobial activity.
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KEYWORD
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Bibenzyl compounds (4), 1D/2D-NMR, mass spectral method, Trichophyton mentagrophytes, antimicrobial activity
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